DOI: 10.25881/20728255_2023_18_4_S1_100

Authors

Uyanaeva A.A., Starostina A.V., Sidorova A.V., Burlakov K.S.

The S. Fyodorov Eye Microsurgery Federal State Institution, Beskudnikovsky Boulevard, Moscow

Abstract

Rationale: Secondary glaucoma in patients after keratoplasty is refractory to many treatment methods, and is also often accompanied by severe comorbid pathology of the eyeball. The choice of a surgical treatment method for such patients causes difficulties for the ophthalmic surgeon, which determines the relevance of this problem.

Objective: To evaluate the effect of surgical treatment of secondary glaucoma in patients after keratoplasty against the background of comorbid pathology (aphakia, aniridia, vitreous hernia, avitria, etc.).

Methods: At the S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, patients with secondary refractory glaucoma after keratoplasty against the background of concomitant pathology were examined and the following was performed: Ahmed valve drainage was implanted in three patients and laser transscleral cyclocoagulation was performed in one patient.

Results: In the postoperative period, after implantation of the Ahmed valve drainage and laser transscleral cyclocoagulation, intraocular pressure was normalized. In patients with Ahmed valve implantation, the drainage tube in the anterior chamber is in the correct position. Up to 12 months after surgery there are no complaints, intraocular pressure is compensated.

Conclusion: The choice of treatment tactics for secondary glaucoma in patients with comorbid pathology after keratoplasty is always individual and is determined by the severity of changes in the structures of the anterior chamber angle, as well as concomitant pathology (aphakia, aniridia, vitreous hernia, avitria, etc.) With pronounced structural changes in the anterior segment of the eye The operations of choice are most often laser transscleral cyclophotocoagulation and implantation of Ahmed valve drainage. The most predicted reduction in intraocular pressure in the early stages after surgery is provided by implantation of the Ahmed valve. Laser transscleral cyclocoagulation is possible both as the first stage and after implantation of the Ahmed valve.

Keywords: secondary glaucoma, Ahmed drainage, intraocular pressure, laser transscleral cyclocoagulation, keratoplasty.

References

1. Oztutuncu O, Altan C, Gumus G, Solmaz B, Basarir B, Alagoz N, Yasar T. Surgical management of glaucoma following different keratoplasty techniques. Int Ophthalmol. 2022 Sep;42(9):2829-2840. doi: 10.1007/s10792-022-02273-x.

2. Abdelghany AA, D’Oria F, Alio JL. Surgery for glaucoma in modern corneal graft procedures. Surv Ophthalmol. 2021 Mar-Apr;66(2):276-289. doi: 10.1016/j.survophthal.2020.08.002.

3. Sidorova A.V., Starostina A.V., Pecherskaia M.A., Stefankova K.A. Advantages of Micropulse Technology as a Method of Choice for the Treatment of Secondary Glaucoma in Patients with Corneal Diseases. Ophthalmology in Russia. 2022;19(3):515-523. Doi: 10.18008/1816-5095-2022-3-515-523.

4. Bernardi E, Töteberg-Harms M. First and second transscleral cyclophotocoagulation treatments provide similar intraocular pressure-lowering efficacy in patients with refractory glaucoma. Int Ophthalmol. 2022 Aug;42(8): 2363-2369. doi: 10.1007/s10792-022-02234-4.

5. Lima F, Magacho L, Carvalho D, Susanna R, Avila M. A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma. J Glaucoma. 2004;13:233–237.

6. Christakis PG, Kalenak JW, Zurakowski D, et al. The Ahmed Versus Baerveldt study: one-year treatment outcomes. Ophthalmology. 2011;118(11): 2180–2189. doi: 10.1016/j.ophtha.2011.05.004.

7. Parihar JK, Jain VK, Kaushik J, Mishra A. Pars Plana-Modified versus Conventional Ahmed Glaucoma Valve in Patients Undergoing Penetrating Keratoplasty: A Prospective Comparative Randomized Study. Curr Eye Res. 2017 Mar;42(3):436-442. doi: 10.1080/02713683.2016.1185130.

8. Akdemir MO, Acar BT, Kokturk F, Acar S. Clinical outcomes of trabeculectomy vs. Ahmed glaucoma valve implantation in patients with penetrating keratoplasty: (Trabeculectomy vs. Ahmed galucoma valve in patients with penetrating keratoplasty). Int Ophthalmol. 2016 Aug;36(4):541-6. doi: 10.1007/s10792-015-0160-9.

For citation

Uyanaeva A.A., Starostina A.V., Sidorova A.V., Burlakov K.S. The choice of method of surgical treatment of secondary glaucoma in patients after keratoplasty using the example of clinical cases. Bulletin of Pirogov National Medical & Surgical Center. 2023;18(4,supplement):100-104. (In Russ.) https://doi.org/10.25881/20728255_2023_18_4_S1_100