Authors
Аntonov A.A. 1, Reshetnikova V.V.2, Dolzhikova Yu.I.2, Solod E.I.1, Lazarev A.F.1, Antonov A.K.3, Gorenkov R.V.3, Simonova A.V.3, Talipov I.A.4
1 N.N. Priorov National Medical Research Center of Traumatology and Orthopedics, Moscow
2 N.N. Blokhin National Medical Research Center of Oncology, Moscow
3 Moscow Regional Research and Clinical Institute («MONIKI»), Moscow
4 Medical College No. 7, Moscow
Abstract
Rationale: In order to predict postoperative infectious complications in patients and their prevention, it is very important to study the markers of inflammation when performing total hip replacement with long-standing trochanter fractures of the femur.
Objective: Study of the inflammation markers dynamics in patients with total hip arthroplasty and old trochanteric fractures in the postoperative period.
Methods: clinical, laboratory, ELISA, statistics.
Results: In patients with postoperative complications elevated levels of C-reactive protein, erythrocyte sedimentation rate and pro-inflammatory cytokines are recorded.
Conclusion: As a result of the studies, it was revealed that the risk factors for the development of postoperative complications are advanced and senile age, comorbid disease and smoking. Elevated levels of C-reactive protein, erythrocyte sedimentation rate, leukocytosis and serum IL-6 may be regarded as significant predictors of inflammatory events in the postoperative period. High levels of IL-8 in the blood suggestive of the manifestations of infectious complications.
Keywords: total hip arthroplasty; inflammation markers; cytokines; old trochanteric fracture.
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