Authors
Batrashov V.A.1, Yashkin M.N.1, Chernov G.A.2, Chernyago T.Yu.1
1 Pirogov National Medical and Surgical Center, Moscow
2 Central Military Clinical Center A.A. Vishnevsky Hospital, Krasnogorsk
Abstract
Angiosarcoma is an extremely rare tumour that is difficult to diagnose and treat. We present a clinical case of a patient admitted to the National Medical and Surgical Center named after N.I. Pirogov with the presumptive diagnosis of thrombophlebitis of the veins of the anterior abdominal wall. The operation was performed: Excision of thrombosed superficial veins of the anterior abdominal wall (hypogastric region) with a positive result. However, a month later, the patient was re-admitted to the vascular surgery department with a worsening condition. It was decided to carry out a second operation with further histological examination, according to the results of which, the patient was diagnosed with angiosarcoma of varicose veins of the anterior abdominal wall. The patient was transferred to a specialized oncological hospital, where he underwent long-term chemotherapy and radiation therapy. With positive dynamics (regression of foci of thrombosed veins in the hypogastric region), the patient was discharged from the hospital, data for the progression of the oncological process were not obtained in the future.
Keywords: angiosarcoma, postthrombotic syndrome, thrombophlebitis, case report.
References
1. Lucas DR. Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion. Arch Pathol Lab Med. 2009; 133(11): 1804–1809. doi: 10.1043/1543-2165-133.11.1804.
2. Kishimoto I, Kikuchi M, Shinohara S, et al. A case of angiosarcoma arising from internal jugular vein. Auris Nasus Larynx. 2015; 42(1): 68–71. doi.org/10.1016/j.anl.2014.08.018.
3. Ibis K, Usta U, Cosar R, et al. Angiosarcoma of common iliac vein. BMJ Case Reports. 2015; bcr2014206103. doi: 10.1136/bcr-2014-206103.
4. Cameliere L, Palcau L, Felisaz A, et al. Intimal Angiosarcoma from the Common Femoral Vein in a 27-Year-Old Patient. Ann Vasc Surg. 2015; 29(2): 364. doi: 10.1016/j.avsg.2014.09.022.
5. Robertson NJ, Halawa MH, Smith ME. Intravascular synovial sarcoma. Int Clin Pathol J. 1998; 51(2): 172–173. doi.org/10.1136/jcp.51.2.172.
6. Fremed DI, Faries PL, Schanzer HR, et al. Primary leiomyosarcoma of saphenous vein presenting as deep venous thrombosis. Vascular. 2014; 22(6): 450–453. doi.org/10.1177/1708538113516446.
7. Greenwald U, Newman E, Taneja S, et al. Malignant epithelioid angiosarcoma of the external iliac vein presenting as venous thrombosis. Ann Vasc Surg. 2004; 18(4): 493–496. doi.org/10.1007/s10016-004-0067-9.
8. Gasparis AP., Wall P, Ricotta JJ. Adventitial cystic disease of the external iliac vein presenting with deep venous thrombosis: a case report. J Vasc Endovasc Surg. 2004; 38(3): 273–276. doi.org/10.1177/153857440403800313.
9. Lin E. Diagnosis of venous angiosarcoma by FDG PET/CT. Clin Nucl Med. 2008; 33(1): 66–67. doi.org/10.1097/RLU.0b013e318148b217.
10. White JS, Medlicott SA, Brown H, et al. Intravascular synovial sarcoma of the external iliac vein and reconstruction with the superficial femoral vein. J Vasc Surg Vasc Sci. 2005; 42(2): 365–367. doi.org/10.1016/j.jvs.2005.03.059.
11. Alosco T, Sinning H, Harwick R, et al. Angiosarcoma of the axillary vein. Cancer. 1989; 64(6): 1301–1303. doi: 10.1002/1097-0142(19890915)64:6<1301::aid-cncr2820640622>3.0.co;2-w.
12. Abratt RP, Williams M, Raff M, et al. Angiosarcoma of the superior vena cava. Cancer. 1983; 52(4): 740–743. doi: 10.1002/1097-0142(19830815)52:4<740::aid-cncr2820520429>3.0.co;2-p.
13. Lang EK, Rudman E, Colon I, et al. Hematuria: the presenting symptom of an angiosarcoma of the inferior vena cava. The Journal of urology. 2009; 182(5): 2470. doi: 10.1016/j.juro.2009.07.099.
14. Casali PG, Abecassis N, Aro HT, et al. Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018; 29(4): 51–67. doi: 10.1093/annonc/mdy096.
