Оценка жизненного цикла нетермальных нетумесцентных методов по Mсkinlay

Маркин С.М.¹, Мазайшвили К.В.², Агаларов Р.М.², Мордовин А.И.¹, Гицук Я.В.¹, Манджикян О.П.³, Густелев Ю.А.²

Цель исследования-выяснить, на каких этапах жизненного цикла медицинских инноваций, согласно модели Маккинли, находятся методы механохимической (МОКа) и цианакрилатной облитерации (САО) и ответить на вопрос: не пора ли большинству флебологов начать использовать их в своей практике? Обзор литературы с использованием базы данных PubMed проводился в том числе с января 2010 года по декабрь 2018 года. Критерием включения была возможность отнести публикацию к любому этапу жизненного цикла. Каждая статья была связана только с одним этапом. Из нашего исследования были исключены экспериментальные исследования на животных, оценивающие безопасность методов, а также статьи, имеющие характер рандомизированных клинических исследований. Исследование включало 93 публикации, 48 из которых были посвящены механохимической абляции, 57-цианоакрилатной облитерации. Распределение статей, описывающих этапы жизненного цикла: Первый этап включал 3 исследования MOCA и 2 исследования CAO; второй этап-14 докладов о механохимической облитерации и 12 публикаций о цианоакрилатной облитерации; третий этап-7 и 14 публикаций соответственно; четвертый этап — 21 для МОКа и 24 для ЦАО; Пятый этап — 3 статьи о МОКа и 5 статей о ЦАО. Никаких публикаций, связанных с шестым и седьмым этапами, не было. Большое количество публикаций, посвященных облитерации цианакрилата, связано с использованием в практике трех видов клея: Вариклозного, Венаблокового и Веназеального. Катетер с режущей кромкой (система Flebogrif) как вариация механохимической облитерации не был представлен в базе данных PubMed, поэтому мы не включили его в наше исследование. Таким образом, нетепловые нетумесцентные методы получили общественное признание и одобрение, а также приобретают черты стандартной процедуры лечения варикозного расширения вен.

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