DOI: 10.25881/20728255_2023_19_1_60

Authors

Botashev R.N.

Karachay-Cherkess Republican Clinical Hospital, Cherkessk

Abstract

Thrombosis of the superficial veins of the lower extremities (thrombophlebitis) is a common pathology, especially in patients with varicose veins. Various methods from anticoagulant therapy to surgical intervention have been proposed and used to treat such patients, but there are still controversial points about their choice.

Aim: to compare the results of surgical treatment of patients with ascending varicothrombophlebitis of the main subcutaneous veins of the lower extremities by radiofrequency ablation and crossectomy.

Materials and methods. The study included the results of treatment of 24 patients (6 (25%) men and 18 (75%) women, the average age of patients was 54±15 years) with varicose veins of the lower extremities class C2-C5 (according to CEAP) and thrombosis of the great saphenous vein and its tributaries. Group I — patients after radiofrequency ablation (n = 12), group II — patients after crossectomy (n = 12). In the postoperative period, the clinical condition and quality of life were assessed according to the CIVIQ-2 questionnaire, control ultrasound examinations were performed 1, 3, 7, 14 days, 1 month and 1 year after surgery.

Results. In the postoperative period, no recurrence of the disease was detected in any of the groups, p>0.005. Lymphorrhea was noted in group II in 16.6% of cases (n = 2), in I this complication was not detected. p<0.005 Parasthesia in patients of group I was detected in 8.3% of cases (n = 1), in Group II in 25% of observations (n = 3), p<0.005. Indicators of the pain factor according to the CIVIQ-2 questionnaire in group I: 1.73±0.93, in group II: 2.8±1.05, p<0.005. In group I, the average bed day was 1.4±0.2 and the duration of disability was 4.9±0.2, in group II — 6.1±1.3 and 13±1.2, respectively (p<0.005).

Conclusion. Surgical methods of treatment of patients with varicose veins of the lower extremities complicated by ascending thrombophlebitis are effective and safe in terms of prevention of venous thrombembolism. Endovenous radiofrequency ablation, being a less traumatic method, avoids general anesthesia, significant cosmetic defects, the development of lymphorrhea, paraesthesia and other complications, especially in obese patients, as well as reduces the time of hospitalization and postoperative rehabilitation.

Keywords: varicose veins, thrombophlebitis, radiofrequency ablation, surgical treatment.

References

1. Duffett L, Kearon C, Rodger M, et al. Treatment of Superficial Vein Thrombosis: A Systematic Review and Meta-Analysis. Thromb Haemost. 2019; 119(3): 479-489. doi: 10.1055/s-0039-1677793.

2. van Royen FS, van Smeden M, Moons KGM, et al. Management of superficial venous thrombosis based on individual risk profiles: protocol for the development and validation of three prognostic prediction models in large primary care cohorts. Diagn Progn Res. 2021; 5(1): 15. doi: 10.1186/ s41512-021-00104-8.

3. Clinical recommendations. Phlebitis and thrombophlebitis of superficial vessels. Phlebology. 2021; 15(3): 211-244. (In Russ.)

4. Bauersachs RM. Oberflächliche Venenthrombose [Superficial Vein Thrombosis]. Dtsch Med Wochenschr. 2021; 146(19): 1237-1242. German. doi: 10.1055/a-1286-2153.

5. Ellis MH, Fajer S. A current approach to superficial vein thrombosis. Eur J Haematol. 2013; 90(2): 85-8. doi: 10.1111/ejh.12044.

6. Marchiori A, Mosena L, Prandoni P. Superficial vein thrombosis: risk factors, diagnosis, and treatment. Semin Thromb Hemost. 2006; 32(7): 737-43. doi: 10.1055/s-2006-951459.

7. Decousus H, Quéré I, Presles E, et al. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med. 2010; 152(4): 218-24. doi: 10.7326/0003-4819-152-4-201002160-00006.

8. Galanaud JP, Sevestre MA, Pernod G, et al. Long-term risk of venous thromboembolism recurrence after isolated superficial vein thrombosis. J Thromb Haemost. 2017; 15(6): 1123-1131. doi: 10.1111/jth.13679.

9. Galanaud JP, Bosson JL, Genty C, et al. Superficial vein thrombosis and recurrent venous thromboembolism: a pooled analysis of two observational studies. J Thromb Haemost. 2012; 10(6): 1004-11. doi: 10.1111/ j. 1538-7836.2012.04704.x.

10. Kurginyan HM, Raskin VV. Endovascular treatment of acute thrombophlebitis of the veins of the lower extremities in patients with varicose veins. Surgery. The journal named after N.I. Pirogov. 2019; 10: 50-54. (In Russ.)

11. Duffett L, Kearon C, Rodger M, et al. Treatment of Superficial Vein Thrombosis: A Systematic Review and Meta-Analysis. Thromb Haemost. 2019; 119(3): 479-489. doi: 10.1055/s-0039-1677793.

12. Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev. 2018; 2(2): CD004982. doi: 10.1002/14651858.CD004982.pub6.

13. Belcaro G, Nicolaides AN, Errichi BM, et al. Superficial thrombophlebitis of the legs: a randomized, controlled, follow-up study. Angiology. 1999; 50(7): 523-9. doi: 10.1177/000331979905000701.

14. Enzler MA, Russell D, Schimmelpfennig J. Thermal ablation in the management of superficial thrombophlebitis. Eur J Vasc Endovasc Surg. 2012; 43(6): 726-8. doi: 10.1016/j.ejvs.2012.02.012.

15. Spinedi L, Stricker H, Staub D, et al. Endovenous Laser Ablation for Treatment of a Partially Thrombosed Proximal Great Saphenous Vein. Case Rep Vasc Med. 2019; 2019: 1726978. doi: 10.1155/2019/1726978.

16. ESC Guidelines for the diagnosis and Treatment of Acute pulmonary embolism, developed in collaboration with the European Respiratory Society (ERS). Russian Journal of Cardiology. 2020; 25(8): 3848. (In Russ.)

17. Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev. 2018; 2(2): CD004982. doi: 10.1002/14651858.CD004982.pub6.

18. Gradman WS. Endovenous saphenous vein ablation in patients with acute isolated superficial-vein thrombosis. Phlebology. 2015; 30(3): 204-9. doi: 10.1177/0268355513514047.

19. Bishara RA, Taha W, Grace AI. Endovenous great saphenous vein ablation for the treatment of superficial thrombophlebitis complicated by pulmonary embolism. European Journal of Vascular and Endovascular Surgery. 2014; 47(3): 330-331. doi: 10.1016/j.ejvs.2013.12.005.

20. Gradman WS. Endovenous saphenous vein ablation in patients with acute isolated superficial-vein thrombosis. Phlebology. 2015; 30(3): 204-209. doi: 10.1177/0268355513514047.

For citation

Botashev R.N. Surgical treatment of patients with varicose veins of the lower extremities complicated by acute ascending thrombosis of the large saphenous vein. Bulletin of Pirogov National Medical & Surgical Center. 2024;19(1):60-63. (In Russ.) https://doi.org/10.25881/20728255_2023_19_1_60