DOI: 10.25881/20728255_2022_17_3_128

Authors

Chuprov A.D., Kuvaitseva Yu.S.

Orenburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg

Abstract

Rationale: Refractory glaucoma is characterized by a high value of intraocular pressure due to a violation of the normal outflow of intraocular fluid and the features of rapid scarring of the anterior chamber angle, the growth of newly formed vessels. The use of intensive maximum antihypertensive therapy in this case is temporary, therefore, it is most advisable to use the method of choice - implantation of an Express shunt, which is directly related to the pathogenesis of the development of this disease.

Objective: to present one of the possible variants for the surgical treatment of advanced refractory glaucoma.

Material and methods. Patient B., 63 years old, was admitted with a diagnosis of open-angle 3 s (drops, operated) refractory unstabilized glaucoma of the left eye; open-angle 1 a (drops) glaucoma of the right eye. According to photo registration of the anterior chamber angle before surgical treatment: anterior chamber angle is open, the degree of pigmentation is -3, pronounced, mixed, multiple goniosynechia of the left eye. According to the instrumental examination, the visual acuity of the right eye (OD) was 0.5 sph (+)1.0 = 1.0; left eye (OS) — 0.1, not corrected. Intraocular pressure measured by the Maklakov method was: OD = 20 mm Hg; OS = 43 mmHg. The following surgical treatment was performed: implantation of an Ex-press shunt on the left eye in a standard way. The implantation was performed at 10 hours due to early surgical treatment in the inner meridian.

Results. On the 1st day after surgical treatment of OS: the position of the eyelids is correct; the movement of the eye is in full. The conjunctiva is hyperemic. The cornea is transparent, shiny, spherical. At 9-10 o’clock the filtering bleb is diffused; the seams are strong. Anterior chamber of medium depth. Ex-press shunt is visualized at 9-10 o’clock. Eye humor is transparent, IOL is in the center. By direct ophthalmoscopy, the fundus of the eye is without dynamics. Postoperative period was without complications. At the control examination after 6 months, the functional data of the left eye remained stable. Perimetry data was without dynamics.

Keywords: advanced glaucoma; refractory glaucoma; Ex-press shunt, gonioscope GS-1.

References

1. Bessmertnyi AM, Erichev VP. Algoritm khirurgicheskogo lecheniya refrakternoi glaukomy. In: Proceedings of Russian research and practical conference «Glaucoma: problems and solution». Moscow, 2004. p.271-272. (In Russ).

2. Shchuko AG, Yur’eva TN, Chekmareva LT, Malyshev VV. Differentsial’naya diagnostika redkikh form glaukomy. Irkutsk: Oblmashinform, 2004. (In Russ).

3. Astakhov YuS, Egorov EA, Astakhov SYu, Brezel YuA. Surgical treatment of refractory glaucoma. Klinicheskaya oftal’mologiya. 2006; 7(1): 25-27 (In Russ).

4. Erichev VP. Refrakternaya glaukoma, osobennosti lecheniya. Vestnik oftal’mologii. 2000; 5: 8-10. (In Russ).

5. Libman ES, Shakhova EV, Chumaeva EA, El’kina YaE. Invalidnost’ vsledstvie glaukomy v Rossii. In: Proceedings of Russian research and practical conference «Glaucoma: problems and solution». Moscow, 2004. Р.430-432. (In Russ).

6. Troyanovskii RL, Sinyavskii OA, Solonina SN, Antipova YuN. Drenirovanie perednei i vitreal’noi kamery posredstvom klapana «Akhmed» pri glaukome u detei i vzroslykh. In: Proceedings of the IX Congress of Ophthalmologists of Russia. Moscow, 2010. P.178. (In Russ).

7. Chudinova OV, Khokkanen VM, Gasyuk LA, Svetlichnaya IV. Drains and valves in refract glaucoma surgery. A clinical case. Oftal’mologiya. 4(2): 25-28. (In Russ).

8. Chuprov AD, Gavrilova IA. Comparative efficacy of application of various drainages in refractive glaucoma. Glaukoma. 2010; 3: 41-44. (In Russ).

9. Al-Aswad LA, Netland PA, Bellows AR, et al. Clinical experience with the double-plate Ahmed glaucoma valve. Am J Ophthalmol. 2006; 141(2): 390-391. doi: 10.1016/j.ajo.2005.08.036.

10. De Giusti A, Pajaro S, Tanito M. Automatic pigmentation grading of the trabecular meshwork in gonioscopic images. In: Computational Pathology and Ophthalmic Medical Image Analysis. (COMPAY-OMIA 2018). Springer International Publishing; 2018: 193-200. doi: 10.1007/978-3-030-00949-6_23.

11. Lima FE, Magacho L, Carvalho DM, et al. A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma . J. Glaucoma. 2004; 13(3): 233-237. doi: 10.1097/00061198-200406000-00011.

12. Malik R, Ellingham RB, Suleman H, Morgan WH. Refractory glaucoma-tube or diode? Clin. Experiment Ophthalmol. 2006; 34(8): 771-777. doi: 10.1111/j.1442-9071.2006.01339.x.

13. Matsuo M, Inomata Y, Kozuki N, Tanito M. Characterization of Peripheral Anterior Synechiae Formation After Microhook Ab-interno Trabeculotomy Using a 360-Degree Gonio-Camera. Clin. Ophthalmol. 2021; 15: 1629-1638. doi: 10.2147/OPTH.S306834.

14. Mistlberger A, Liebmann JM, Tschiderer H, et al. Diode laser transscleral cyclophotocoagulation for refractory glaucoma. J. Glaucoma. 2001; 10(4): 288-293. doi: 10.1097/00061198-200108000-00008.

15. Nassiri N, Kamali G, Rahnavardi M, et al. Ahmed glaucoma valve and single-plate Molteno implants in treatment of refractory glaucoma: a comparative study. Am. J. Ophthalmol. 2010; 149(6): 893-902. doi: 10.1016/j.ajo.2010.01.025.

16. Yue Sh, Xin Y, Kenneth MM, et al. Novel and semiautomated 360-degree gonioscopic anterior chamber angle imaging in under 60 seconds // Ophthalmology Glaucoma. 2019; 2(4): 215–223. doi: 10.1016/j.ogla.2019.04.002.

For citation

Chuprov A.D., Kuvaitseva Yu.S. Clinical case of surgical treatment of advanced refractory glaucoma. Bulletin of Pirogov National Medical & Surgical Center. 2022;17(3):128-130. (In Russ.) https://doi.org/10.25881/20728255_2022_17_3_128