Authors
Kabanov M.Yu.1, 2, Semencov K.V.1, 2, Polikarpov A.V.1, Besedin I.I.2
1 Hospital for veterans of wars, Saint-Petersburg
2 NWSMU named after I.I. Mechnikov, St. Petersburg
Abstract
The article deals with the current state of the problem of fractures of the proximal femur in elderly and senile patients. Among a large number of patients in this age group, there are high risk of developing infection in the area of surgical intervention after hip arthroplasty. The importance of using NPWT in the treatment and prevention of surgical site infection in older patients with polymorbid pathology in emphasized.
Keywords: femur neck fracture, NPWT, surgical site infection, prevention of infection.
References
1. Irugova EZ, Mukhamadieva LB, Midov AZ, Saubanova RK. Fractures of the femoral neck in the structure of combined trauma. Bulletin of the Young scientist. 2020; 9(1): 3-5. (In Russ).
2. Agadzhanyan VV, Pronskikh AA, Evsyukov AV, et al. Tactics of treatment of fractures of the proximal femoral in elderly and senile patients. In.: IX congress of traumatologists-orthopedists of Russia; Saratov, 2010; (1): 74-75. (In Russ).
3. Bronstein AS, Lutsevich OE, Rivkina VL, Zelenina AV. Elderly Surgical Patient: A Guide for Physicians. 2012: 17-19, 42-43. (In Russ).
4. Roberts KS, Brooks VV, Evseeva DS, Severino K. Treatment of femoral neck fractures in the elderly. About Am Acad Orthop Surg. 2015; 23(2): 131-7.
5. Chammout G, Murano, Laurencikas E, Body H, Kelly-Paterson P, Sjöö H, et al. There are more complications with uncemented than with cement legs of the femur in total hip replacement with hip neck fractures with displacement in the elderly. Acta Orthop. 2017; 88(2): 145–51.
6. Maja L, PiattiA, Pecoraro V, Ricci C, Virgili G, Salanti G, etc. In hip fracture surgery, time is important: patients operated on within 48 hours have the best results. Meta-analysis and meta-regression of more than 190,000 patients. PLoS One. 2012; 7(10): e46175.
7. Lewis PM, Waddell JP. When is the best time to operate on a patient with a hip fracture? Review of the available literature. Bone Joint J. 2016; 98-B(12): 1573-81.
8. Coleman M, Wright A, Green G, Sicca P, Page HC, Tarkin I. A long operation time increases the frequency of infection in fractures of the tibial plateau. Injury, damage. 2013; 44(2): 249-52.
9. Izakovikova P, Berens O, Trumpuz A. Infection of the periprosthetic joint: modern concepts and perspectives. EFORT Open Rev.2019; 4(7): 482-94.
10. Noailles T., Brulefert K, Chalopin A, Long is PM, Goin F. What are the risk factors for postoperative infection after hip hemiarthroplasty? A systematic review of the literature. Int Orthop. 2016; 40(9): 1843-8.
11. Belov MV, Degtyarev AA, Ershova OB, et al. Experience of early surgical treatment of patients with osteoporotic fractures of the proximal femur. Osteoporosis and osteopathy. 2020; 23(1): 49-50. (In Russ).
12. Carres J, Kievyet N, Ehrenberg JP, Wrowenraetz BC. Predicting Early Mortality After Hip Fracture Surgery: Estimating Hip Fracture Mortality, Amsterdam. J Orthop Trauma. 2018; 32(1): 27-33.
13. Roberta E, Redfern Ph, Da Claire Cameron-Ruetzb, Simone K, O’Drobinak PA-Cc, John T, Chen PhDd, Karl J, Beer MDc. Closed Incision Negative Pressure Therapy Effects on Postoperative Infection and Surgical Site Complication After Total Hip and Knee Arthroplasty. The Journal of Arthroplasty. 2017; 32(11): 3333-3339.
14. Berstock JR, Beswick AD, Lenguerrand E, Whitehouse MR, Blom AW. Mortality after total hip replacement surgery: a systematic review. Bone Joint Res. 2014; 3: 175-82. doi: 10.1302/2046-3758.36.2000239.
15. Smith T, Pelpola K, Ball M, Ong A, Myint PK. Pre-operative indicators for mortality following hip fracture surgery: a systematic review and meta-analysis. Age Ageing 2014; 43: 464-71.
16. Belmont PJ Jr, Goodman GP, Hamilton W, Waterman BR, Bader JO, Schoenfeld AJ. Morbidity and mortality in the thirty-day period following total hip arthroplasty: risk factors and incidence. J Arthroplasty 2014; pii: S0883-5403(14)00356–8. doi: 10.1016/j.arth.2014.05.015.
17. Horch RE, Gerngross H, Lang W, Mauckner P, Nord D, Peter RU, Vogt PM, Wetzel-Roth W, Willy C. Indications and safety aspects of vacuum-assisted wound closure. MMW Fortschr Med. 2005; 147(1): 1-5.
18. Willy C, von Thun-Hohenstein H, von Lubken F, Weymouth M, Kossmann T, Engelhardt M. Experimental principles of the V.A.C.-therapy — pressure values in superficial soft tissue and the applied foam. Zentralbl Chir. 2006; 131(1): 50-61.
19. Endo A, Baer HJ, Nagao M, Weaver MJ. Model for the prognosis of hospital mortality after surgical treatment of a hip fracture. J Orthop Trauma. 2018; 32(1): 34-38.
20. Clark RA. Fibrin is a many splendored thing. J Invest Dermatol 121: xxi–xxii, 2003. doi:10.1046/j.1523-1747.2003.12575.x.
21. Kong HH, Segre JA. Skin microbiome: looking back to move forward. J Invest Dermatol. 2012; 132: 933-939. doi:10.1038/jid.2011.417.
22. Wilgus TA, Roy S, McDaniel JC. Neutrophils and Wound Repair: Positive Actions and Negative Reactions. Adv Wound Care (New Rochelle). 2013; 2: 379-388. doi:10.1089/ wound.2012.0383.
23. Park JE, Barbul A. Understanding the role of immune regulation in wound healing. Am J Surg. 2004; 187(5A): 11S-16S. doi:10.1016/S0002-9610 (03)00296-4.
24. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast. Surg. 1997; 38: 563-76.
25. Ubbink DT, Westerbos SJ, Evans D, Land L, Vermeulen H. Topical negative pressure for treating chronic wounds. Cochrane Database Syst Rev. 2008. 3: CD001898. doi: 10.1002/14651858.
26. McNulty AK, Schmidt M, Feeley T, Villanueva P, Kieswetter K. Effects of negative pressure wound therapy on cellular energetics in fibroblasts grown in a provisional wound (fibrin) matrix. Wound Repair Regen 2009; 17: 192-9. PMID: 19320887.
27. Zaitseva EL, Tokmakova AYu. Vacuum therapy in the treatment of chronic wounds. Diabetes mellitus. 2012; 3: 45-9. (In Russ).
28. Nikitin VG, Obolensky VN, Semenisty AYu, Sychev DV. Vacuum therapy in the treatment of wounds and wound infection. Journal Russian medical. 2010; 17: 1064-1072. (In Russ).
29. Abramov AYu. Vacuum therapy in the regulation of the wound process in elderly and senile patients. [dissertation.] Yaroslavl; 1992. (In Russ).
30. Russu II, Linnik SA, Tkachenko AN, et al. The use of vacuum therapy in the treatment of periprosthetic infection after arthroplasty of the hip joint. Journal of scientific articles Health and education in the XXI century. 2017; 19(8): 50-54. (In Russ).
31. Russu II, Linnik SA, Tkachenko AN, et al. Application of the method of local negative pressure in the complex treatment of early periprosthetic infection after hip arthroplasty. Vestn Khir Im I I Grek. 2016. 177(1): 41-44. (In Russ). doi: 10.24884 / 0042-4625-2018-177-1-41-44.
32. Kaplan M, Daly D, Stemkowski S. Early intervention of negative pressure wound therapy using vacuum-assisted closure in trauma patients: impact on hospital length of stay and cost. Adv Skin Wound Care. 2009; 22: 128-32.
33. Horch RE, Münchow S, Dragu A. Erste Zwischenergebnisse der Perfusionsbeeinflussung durch Prevena: Gewebsperfusionsmessung. Zeitschrift für Wundheilung. 2011; A16: 19-20.
34. Pauser J, Nordmeyer M, Bieber R, Jan J, Kopschina S, Bel HJ, Brem MH. Postoperative therapy of wounds with negative pressure after hemiarthroplasty for hip fractures-reduction of wound complications. Int J Wound. 2014; August 14.
35. Pitto RP, Sedel L. Periprosthetic joint infection in hip arthroplasty: is there a relationship between infection and bearing surface type? Clin. Orthop. Relat. Res. 2016; 474: 2213-2218.
36. Gomoll AH, Line, Harris MB. Postoperative closing therapy using a vacuum. J Orthop Trauma. 2006; 20: 705-709.
37. Reddick RN, Len XI, Woodall J, Jackson B, Dedmond B, Webb LX. The effect of postoperative negative pressure therapy on wound complications after acetabulum fracture surgery. J Surg Orthop Adv. 2010; 19: 91-7.
38. Stannard JP, Robinson JT, Anderson ER, McGavin J, Volga DA, Alonso JE. Negative pressure wound treatment for the treatment of hematomas and surgical incisions after high-energy trauma. J Trauma. 2006; 60: 1301-6.
39. Ansell DM, Izeta A. Pericytes in wound healing: friend or foe? Exp Dermatol. 2015; 24: 833-834. doi:10.1111/exd.12782.
40. Garro O, Hosein VN, Badr G. Wound healing: time to look for intelligent, “natural” immunological approaches? BMC Immunol. 2017; 18: 23.
41. Ansari S, Hassan M, Barry HD, et al. Risk factors associated with surgical site infections: a retrospective report from a developing country. Cureus. 2019; 11(6): e4801.
42. Gould L, Abadir P, Brehm X, et al. Healing and healing of chronic wounds in the elderly: current status and future research. Regeneration of wound recovery. 2015; 23(1): 1-13.
43. Kirchner S, Lei V, MacLeod AS. The Cutaneous Wound Innate Immunological Microenvironment. Int J Mol Sci. 2020; 21(22): 8748.