Authors
Evtushenko A.A.4, Krajnyukov P.E.1, 2, Kokorin V.V.1, 3, Vahaev D.S.3
1 Central Military Clinical Hospital. P.V. Mandryka, Moscow
2 RUDN University, Moscow
3 Pirogov National Medical and Surgical Center, Moscow
4 422 Military Hospital of the Ministry of Defense, Nizhny Novgorod
Abstract
At present, the choice of the optimal approach in the treatment of patients suffering from enthesopathies of various localization, as well as the reduction of the terms of their rehabilitation, remains an urgent and significant medical and social problem of modern society. The problem affects most of the population during life and covers all areas of work. Lack of generally accepted standards of treatment, delayed diagnosis, long-term and persistent nature of the disease, cause ambiguous outcomes and a high percentage of relapses, leads to neglect of the process, deterioration of the quality of life of patients and disability of the working population.
The article discusses the methods of regenerative therapy used in the treatment of patients with enthesopathies. The analysis of the characteristics of the use of modern techniques is carried out and the possible terms of rehabilitation of patients are reflected.
Keywords: enthesis, enthesopathy, regeneration, auto tissue, rehabilitation.
References
1. Balabanova RM. Enthesitis: diagnosis and treatment. Russian Medical Journal. 2012; 11: 538. (In Russ).
2. Dennis MG, Kay-Geert AH, Ai LT. Differentiation between osteoarthritis and psoriatic arthritis: implications for pathogenesis and treatment in the biologic therapy era. Rheumatology. 2015; 54(1): 29-38.
3. Juneja SC, Veillette C. Defects in Tendon, Ligament, and Enthesis in Response to Genetic Alterations in Key Proteoglycans and Glycoproteins: A Review. Arthritis. 2013: 154812: doi. 10.1155/2013/154812.
4. Wang X, Xie L, Crane J, et al. Aberrant TGF-β activation in bone tendon insertion induces enthesopathy — like disease. Journal of Clinical Investigation. 2018; 128(2): 846-860.
5. Khitrov NA. Paraartikulyarnyye tkani: varianty porazheniya i ikh lecheniye. Russian medical journal. 2017; 3: 177-187. (In Russ).
6. Zagorodnyy GM, Karpenkov KM, Tikhonenkov AA, Yasyukevich AS. Osobennosti primeneniya preparatov gialuronana vnutrisustavno v sportivnoy praktike. Medical News. 2014. №11(242): 69-73. (In Russ).
7. Yasyukevich AS, Gulevich NP, Mukha PG. Analiz urovnya i struktury sluchayev sportivnogo travmatizma v otdel’nykh vidakh sporta. Applied sports science. 2016; 1(3): 89-99. (In Russ).
8. Kokorin VV, Kuz’min DB, Kraynyukov PYe, Yepifanov SA. Rol’ infektsii v etiopatogeneze entezopatiy. Bulletin of the National Medical and Surgical Center N.I. Pirogov. 2020; 15(3): 141-149. (In Russ).
9. Arend CF. Role of sonography and magnetic resonance imaging in detecting deltoideal acromialenthesopathy: an early finding in the diagnosis of spondyloarthritis and an under-recognized cause of posterior shoulder pain. Journal of ultrasound in medicine. 2014; 33(4): 557-61.
10. Karateyev AY, Karateyev DY, Orlova YS, et al. «Malaya» revmatologiya: nesistemnaya revmaticheskaya patologiya okolosustavnykh myagkikh tkaney verkhney konechnosti. Chast’ 1. Modern rheumatology. 2015; 9(2): 4-15. (In Russ).
11. Godzenko AA. Lechenie periartikuljar-nyh bolevyh sindromov. Russian medical journal. 2012; 7: 382-384. (In Russ).
12. Malakhov NB, Pykov MI, Chochiyev GM. Normal’naya ekhoanatomiya paraartikulyarnykh tkaney kolennogo sustava u detey i metodika ikh ul’trazvukovogo obsledovaniya. Ultrasound and functional diagnostics. 2002; 2: 101-111. (In Russ).
13. Ivanova ON, Sobolev YuA, Pyadova YeA, et al. Sravnitel’nyy analiz artrosonograficheskikh i rentgenograficheskikh izmeneniy sustavov pri revmaticheskikh zabolevaniyakh. Nauchno-prakticheskaya revmatologiya. 2004; 4: 11. (in Russ).
14. Adzhigaytkanova SK. Diagnostika i lecheniye otdel’nykh form revmaticheskikh zabolevaniy s pozitsii dokazatel’noy meditsiny. Study guide. 2013. P.6-23. (In Russ).
15. Akhmerov RR. Primeneniye tekhnologii Pasmolifting v travmatologii i vosstanovitel’noy meditsine. // R.R. Akhmerov, R.F. Zarudiy, F.R. Khayrullin // Collection of guidelines. M. 2016. P. 24-33. (In Russ).
16. Teplov OV, Teplova YuS, Plakseychuk YuA, et al. Metodika primeneniya autologichnoy bogatoy trombotsitami plazmy v lechenii patsiyentov c osteoartrozom kolennykh sustavov. Guidelines. Kazan. 2017. (In Russ).
17. Wu, P.I. Platelet-rich plasma / P.I. Wu, R. Diaz, J. Borg-Stein // Physical Medicine and Rehabilitation Clinics of North America. — 2016. — № 27(4). — P. 825-853.
18. Intraoperative application platelet rich fibrin, postoperative injections of PRP or microfracture only for osteochondral lesions of the knee: a five-year retrospective evaluation / R. Papalia , L. Diaz Balzani, G. Torre, M.C. Tirindelli et al. // Journal of biological regulators & homeostatic agents. — 2016. — № 30(4). — P. 41-49.
19. Hyaluronic acid versus platelet-rich plasma: a prospective, double-blind randomized controlled trial comparing clinical outcomes and effects on intraarticular biology for the treatment of knee osteoarthritis // B.J. Cole, V. Karas, K. Hussey, K. Pilz. // American Journal of Sports Medicine. — 2017. — № 45(2). — P. 339-346.
20. PRP for degenerative cartilage disease / L. Laver, N. Marom, L. Dnyanesh, O. Mei-Dan et al. // Cartilage. — 2016. — № 1.
21. Platelet-rich plasma injections for advanced knee osteoarthritis: a prospective, randomized, double-blinded clinical trial / N. Joshi Jubert, L. Rodríguez, M.M. Reverté-Vinaixa, A. Navarro // Orthopaedic journal of sports medicine. — 2017. — № 5(2).
22. D’souza N., Rossignoli F., Golinelli G., Grisendi G., Spano C., Candini O., Dominici M. Mesenchymal stem/ stromal cells as a delivery platform in cell and gene therapies. // BMC Medicine. — 2015. — Vol. 13(1). –186 p.
23. Ennis W.J., Sui A., Bartholomew A. Stem cells and healing: impact on inflammation. // Advances in Wound Care. — 2013. — Vol. 2(7). — P. 369-378.
24. Fodor P.B., Paulseth S.G. Adipose derived stromal cell (ADSC) injections for pain management of osteoarthritis in the human knee joint. // Aesthetic Surgery Journal. — 2015. — Vol. 36(2):229-236.
25. Ude C.C., Sulaiman S.B., Min-Hwei N., Hui-Cheng C., Ahmad J., Yahaya N.M., Saim A.B., Idrus R.B.H. Cartilage regeneration by chondrogenic induced adult stem cells in osteoarthritic sheep model. // PLoS One. — 2014. — Vol. 9(6):e98770. doi: 10.1371/journal.pone.0098770.
26. Bourin P., Bunnell B.A., Casteilla L., Dominici M., Katz A.J., March K.L., Redl H., Rubin J.P., Yoshimura K., Gimble J.M. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). // Cytotherapy. — 2013. — Vol. 15(6):641-648.
