Authors
Orlov A.M.1, Popkova N.G.1, Galimov M.L.1, Danilova V.A.1, Taskaeva E.I.1, Zhiburt E.B.2
1 Regional blood transfusion station, Ekaterinburg
2 Pirogov National Medical and Surgical Center, Moscow
Abstract
The clinical efficacy of transfusion of anticovid plasma was evaluated. From April 27 to May 29, 2020, 28 donations were made; 75 therapeutic units of anticovid plasma were prepared for delivery. 40 units of anticovid plasma have been issued for transfusion. Clinicians were asked to fill out an original transfusion efficacy questionnaire. We received 24 completed questionnaires (60%), the analysis of which found that transfusion of anticovid plasma is well tolerated and in 54% of recipients leads to an improvement in the course of the disease within 24 hours. All plasma recipients received the recommended comprehensive treatment. Therefore, to isolate a plasma-specific therapeutic effect, randomized trials with control groups are required — a) without plasma transfusion and b) with transfusion of a healthy donor’s plasma.
Keywords: plasma, transfusion, anticovid, efficacy, infection, COVID-19.
References
1. Kuznecov SI, Kudinova EV, Zhiburt EB. Zagotovka krovi v period infekcii COVID-19. Menedzher zdravoohranenija. 2020; (5): 41–44. (In Russ).
2. Zhiburt EB. Sluzhba krovi Pirogovskogo centra: vchera, segodnya, zavtra. Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2006; 1(1): 55–57. (In Russ).
3. Zhiburt EB, Madzaev SR, Shestakov EA, Fajbushevich AG, Protopopova EB. Medicinskaja i jekonomicheskaja jeffektivnost’ ogranichitel’noj strategii perelivanija krovi. Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2015; 10(1): 100–102. (In Russ).
4. Zhiburt EB, Gubanova MN, Shestakov EA, Ismailov HG. Potrebnost’ kliniki v komponentah krovi izmenyaetsya. Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2008; 3(1): 60–67. (In Russ).
5. Zhiburt EB. Nasha normativnaja baza poka ne predusmatrivaet perelivanie kakoj by to ni bylo immunnoj plazmy. Spravochnik zavedujushhego KDL. 2020; 6: 10–13. (In Russ).
6. Vremennye metodicheskie rekomendacii. Profilaktika, diagnostika i lechenie novoj koronavirusnoj infekcii (COVID-19). 7th version. 03.06.2020. (In Russ).
7. Zhiburt EB, Maksimov VA, Vecherko AV. et al. Sovershenstvovanie infekcionnoj bezopasnosti i organizacii sluzhby krovi. Vestnik Nacional’nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2007; 2(2):63–67. (In Russ).
