Authors
Staroverov I.N.1, 2, Noshchenko N.S.1, 2, SHubin L.B.1
1 Yaroslavl State Medical University, Yaroslavl
2 Regional Clinical Hospital, Yaroslavl
Abstract
The study addresses the problem of thrombosis of native vascular access in patients with end-stage renal failure. The aim of the work was to identify the features of laboratory changes in patients on programmed hemodialysis correlated to functioning of vascular access to determine the risk factors of thrombosis of access. The results of treatment of 168 patients with native arteriovenous radiotsephalic fistula were analyzed. On a monthly basis during the entire observation period, patients’ indicators were monitored under the protocol of managing a patient receiving renal replacement therapy. The results of treatment within 1 year were tracked. According to the observation results, patients were divided into 2 groups: the 1st group - patients who did not develop thrombosis of an arteriovenous fistula for 1 year of hemodialysis, and the 2nd group – patients who had a vascular access due to thrombosis during the first year. Risk factors which affect the occurrence of thrombosis of an arteriovenous fistula were revealed by comparing the studied groups. Degree and direction of influence of the identified factors were determined during the analysis of correlation between these risk factors and occurrence of thrombosis. Based on the results of the study, it can be concluded that the systematic correction of the identified indicators in patients receiving renal replacement therapy through program hemodialysis can reduce the percentage of thrombosis of vascular access.
Keywords: arteriovenous fistula, thrombosis, hemodialysis, chronic renal failure, vascular access.
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